Chronic Kidney Disease is recognized as a major health problem affecting approximately 13% of the population. Chronic Kidney Disease (CKD) is defined as either kidney damage or glomerular filtration rate (GFR) <_60 ml/min/1.73m2 for at a period of 3 months or more. Kidney damage is characterized by structural or functional abnormalities, with or without decreased GFR, and is manifested either by pathological abnormalities or markers of kidney damage including abnormalities in the composition of blood or urine, or abnormalities in imaging tests. A 55 year old moderately built male patient diagnosed case of CKD was admitted in Taranath Government Ayurvedic Medical College and hospital on 2nd August 2021.The patient was complaining of Dourbalya (weakness), Pandu (Anemia), Padashotha (pedal edema), Arohana ayasa (Exertional dyspnoea), Swasakrichrata (Breathlessness) for 9 years which was gradual in onset. Investigations done before treatment. Hareetakyadi yoga does urdhwa adho shodhana because it contains vacha, pippali, saindhava does urdwa shodhana, Haritaki does vatanulomana this will enhance bio availability of the drugs because shodhana helps in removing the free radicals present in the micro circulatory channels. All the drugs in the formulation Pathyapunarnavadi churna are shophahara, this property helps to eliminate the kleda sanchaya in body, and accumulation of kleda is one of the important factors in the samprapthi of CKD. Rasayana guna of drugs in the formulation helps in maintaining the integrity of dhathu and dhathuvaha srothas.
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